Загрузка...
TRIM24 Is a p53-Induced E3-Ubiquitin Ligase That Undergoes ATM-Mediated Phosphorylation and Autodegradation during DNA Damage
Tumor suppressor p53 protects cells from genomic insults and is a target of mutation in more than 50% of human cancers. Stress-mediated modification and increased stability of p53 promote p53 interaction with chromatin, which results in transcription of target genes that are critical for the mainten...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2014
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097665/ https://ncbi.nlm.nih.gov/pubmed/24820418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01705-12 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|