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E2F Activators Signal and Maintain Centrosome Amplification in Breast Cancer Cells
Centrosomes ensure accurate chromosome segregation by directing spindle bipolarity. Loss of centrosome regulation results in centrosome amplification, multipolar mitosis and aneuploidy. Since centrosome amplification is common in premalignant lesions and breast tumors, it is proposed to play a centr...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097658/ https://ncbi.nlm.nih.gov/pubmed/24797070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01688-13 |
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