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Aggregation Interplay between Variants of the RepA-WH1 Prionoid in Escherichia coli

The N-terminal domain (winged-helix domain, or WH1) of the Pseudomonas pPS10 plasmid DNA replication protein RepA can assemble into amyloid fibers in vitro and, when expressed in Escherichia coli, leads to a unique intracellular amyloid proteinopathy by hampering bacterial proliferation. RepA-WH1 am...

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Autors principals: Molina-García, Laura, Giraldo, Rafael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097580/
https://ncbi.nlm.nih.gov/pubmed/24794561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01527-14
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