RepA-WH1 prionoid: Clues from bacteria on factors governing phase transitions in amyloidogenesis

In bacterial plasmids, Rep proteins initiate DNA replication by undergoing a structural transformation coupled to dimer dissociation. Amyloidogenesis of the ‘winged-helix’ N-terminal domain of RepA (WH1) is triggered in vitro upon binding to plasmid-specific DNA sequences, and occurs at the bacteria...

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Publicado en:Prion
Main Authors: Giraldo, Rafael, Fernández, Cristina, Moreno-del Álamo, María, Molina-García, Laura, Revilla-García, Aída, Sánchez-Martínez, María Cruz, Giménez-Abián, Juan F., Moreno-Díaz de la Espina, Susana
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981189/
https://ncbi.nlm.nih.gov/pubmed/27040981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1129479
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