Outlining Core Pathways of Amyloid Toxicity in Bacteria with the RepA-WH1 Prionoid

The synthetic bacterial prionoid RepA-WH1 causes a vertically transmissible amyloid proteinopathy in Escherichia coli that inhibits growth and eventually kills the cells. Recent in vitro studies show that RepA-WH1 builds pores through model lipid membranes, suggesting a possible mechanism for bacter...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Molina-García, Laura, Moreno-del Álamo, María, Botias, Pedro, Martín-Moldes, Zaira, Fernández, María, Sánchez-Gorostiaga, Alicia, Alonso-del Valle, Aída, Nogales, Juan, García-Cantalejo, Jesús, Giraldo, Rafael
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378768/
https://ncbi.nlm.nih.gov/pubmed/28421043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00539
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