Substitution at Aspartic Acid 1128 in the SARS Coronavirus Spike Glycoprotein Mediates Escape from a S2 Domain-Targeting Neutralizing Monoclonal Antibody

The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is the etiological agent for the infectious disease, SARS, which first emerged 10 years ago. SARS-CoV is a zoonotic virus that has crossed the species barriers to infect humans. Bats, which harbour a diverse pool of SARS-like CoVs (SL-CoVs...

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Main Authors: Ng, Oi-Wing, Keng, Choong-Tat, Leung, Cynthia Sau-Wai, Peiris, J. S. Malik, Poon, Leo Lit Man, Tan, Yee-Joo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097068/
https://ncbi.nlm.nih.gov/pubmed/25019613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102415
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