CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition.
Binding of the lipid A portion of bacterial lipopolysaccharide (LPS) to leukocyte CD14 activates phagocytes and initiates the septic shock syndrome. Two lipid A analogs, lipid IVA and Rhodobacter sphaeroides lipid A (RSLA), have been described as LPS-receptor antagonists when tested with human phago...
Збережено в:
| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
1995
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.20.9288 |
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