CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition.

Binding of the lipid A portion of bacterial lipopolysaccharide (LPS) to leukocyte CD14 activates phagocytes and initiates the septic shock syndrome. Two lipid A analogs, lipid IVA and Rhodobacter sphaeroides lipid A (RSLA), have been described as LPS-receptor antagonists when tested with human phago...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Delude, R L, Savedra, R, Zhao, H, Thieringer, R, Yamamoto, S, Fenton, M J, Golenbock, D T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.20.9288
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