Comparing strategies to fine map the association of common SNPs on chromosome 9p21 to Type 2 Diabetes and Myocardial Infarction

Non-coding variants at human chromosome 9p21 near CDKN2A and CDKN2B are associated with type 2 diabetes (T2D)(1-4), myocardial infarction (MI)(5-7), aneurysm(8), vertical cup disc ratio(9), and at least five cancers(10-16). We compared approaches to more comprehensively assess genetic variation in t...

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Main Authors: Shea, Jessica, Agarwala, Vineeta, Philippakis, Anthony A., Maguire, Jared, Banks, Eric, DePristo, Mark, Thomson, Brian, Guiducci, Candace, Kathiresan, Sekar, Gabriel, Stacey, Burtt, Noël P, Daly, Mark J., Groop, Leif, Altshuler, David
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096898/
https://ncbi.nlm.nih.gov/pubmed/21775993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.871
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