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The subtle benefits of being promiscuous: adaptive evolution potentiated by enzyme promiscuity

In this commentary we discuss recent progress in our understanding of adaptive protein evolution. We begin with a general introduction to proteins and their evolution, quickly focusing on the question of how natural selection produces proteins with novel functions. We then summarize the theory of la...

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Bibliografiske detaljer
Hovedforfatter: DePristo, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: HFSP Publishing 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639842/
https://ncbi.nlm.nih.gov/pubmed/19404414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2976/1.2754665
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