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Implementation of Validated Pharmacodynamic Assays in Multiple Laboratories: Challenges, Successes, and Limitations

There is a “life-cycle” of pharmacodynamic (PD) biomarker assays that guides the development and clinical implementation in our laboratories. The well-recognized elements of analytical assay validation and demonstration of fitness-for-purpose of the biomarker, specimen collection, handling and assay...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kinders, Robert, Ferry-Galow, Kate, Wang, Lihua, Srivastava, Apurva K., Ji, Jiuping (Jay), Parchment, Ralph E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096894/
https://ncbi.nlm.nih.gov/pubmed/24831280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0476
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