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Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a highly-abundant nuclear long noncoding RNA that promotes malignancy. A 3′-stem-loop structure is predicted to confer stability by engaging a downstream A-rich tract in a triple helix, similar to the expression and nuclear retention...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096706/ https://ncbi.nlm.nih.gov/pubmed/24952594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2844 |
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