Conservation of a Triple-Helix Forming RNA Stability Element in Noncoding and Genomic RNAs of Diverse Viruses

Abundant expression of the long noncoding (lnc) PAN (polyadenylated nuclear) RNA by the human oncogenic gammaherpesvirus KSHV depends on a cis-element called the ENE. The ENE upregulates PAN RNA by inhibiting its rapid nuclear decay through triple-helix formation with the poly(A) tail. Using structu...

Full description

Saved in:
Bibliographic Details
Main Authors: Tycowski, Kazimierz T., Shu, Mei-Di, Borah, Sumit, Shi, Mary, Steitz, Joan A.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430378/
https://ncbi.nlm.nih.gov/pubmed/22840393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.05.020
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items