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Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice

Clostridium difficile associated diarrhea (CDAD) is a critical public health problem worldwide with over 300,000 cases every year in the United States alone. Clearly, a potent vaccine preventing the morbidity and mortality caused by this detrimental pathogen is urgently required. However, vaccine ef...

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מידע ביבליוגרפי
Main Authors: Seregin, Sergey S., Aldhamen, Yasser A., Rastall, David P.W., Godbehere, Sarah, Amalfitano, Andrea
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096697/
https://ncbi.nlm.nih.gov/pubmed/22200503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.064
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