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HIGH FAT DIET INDUCED HEPATIC STEATOSIS AND INSULIN RESISTANCE: ROLE OF DYSREGULATED CERAMIDE METABOLISM
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is an insulin resistance disease that can progress to cirrhosis or liver failure. HYPOTHESIS: In NAFLD, insulin resistance dysregulates lipid metabolism, increasing production of cytotoxic lipids including ceramides, which exacerbate hepatic insu...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096625/ https://ncbi.nlm.nih.gov/pubmed/22176347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1872-034X.2011.00934.x |
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