Chronic Ingestion of H1-Antihistamines Increase Progression of Atherosclerosis in Apolipoprotein E-/- Mice

Although increased serum histamine levels and H1R expression in the plaque are seen in atherosclerosis, it is not known whether H1R activation is a causative factor in the development of the disease, or is a host defense response to atherogenic signals. In order to elucidate how pharmacological inhi...

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Main Authors: Raveendran, Vineesh V., Smith, Donald D., Tan, Xiaoyu, Sweeney, Matthew E., Reed, Gregory A., Flynn, Colleen A., Tawfik, Ossama W., Milne, Ginger, Dileepan, Kottarappat N.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096593/
https://ncbi.nlm.nih.gov/pubmed/25020133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102165
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