REGULATION OF THE EXPRESSION OF CYCLOOXYGENASES AND PRODUCTION OF PROSTAGLANDIN I(2) AND E(2) IN HUMAN CORONARY ARTERY ENDOTHELIAL CELLS BY CURCUMIN

Curcumin regulates prostaglandin (PG) synthesis in a variety of cells. PGE(2) and PGI(2) are generated from arachidonic acid (AA) by cyclooxygenases 1 and 2 (COX-1 and COX-2) and the synthase (PGES and PGI(2)S) pathways. This study evaluates the in vitro effect of curcumin on the expression of COX-1...

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Main Authors: Tan, Xiaoyu, Poulose, Ellen M., Raveendran, Vineesh V., Zhu, Bao-Ting, Stechschulte, Daniel J., Dileepan, Kottarappat N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503245/
https://ncbi.nlm.nih.gov/pubmed/21451206
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