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INCREASED AORTIC ATHEROSCLEROTIC PLAQUE DEVELOPMENT IN FEMALE APOLIPOPROTEIN E-NULL MICE IS ASSOCIATED WITH ELEVATED THROMBOXANE A(2) AND DECREASED PROSTACYCLIN PRODUCTION

The production of thromboxane A(2) (TXA(2)) and prostacyclin (prostaglandin I(2), PGI(2)) is known to be increased in patients with atherosclerosis. In this study, we evaluated the influence of gender on TXA(2) and PGI(2) production and their association with the progression of atherosclerosis in ap...

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Detalhes bibliográficos
Main Authors: Smith, Donald D., Tan, Xiaoyu, Tawfik, Ossama, Milne, Ginger, Stechschulte, Daniel J., Dileepan, Kottarappat N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515053/
https://ncbi.nlm.nih.gov/pubmed/20610861
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