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In Silico Investigation of Potential Pyruvate Kinase M2 Regulators from Traditional Chinese Medicine against Cancers

A recent research in cancer research demonstrates that tumor-specific pyruvate kinase M2 (PKM2) plays an important role in chromosome segregation and mitosis progression of tumor cells. To improve the drug development of TCM compounds, we aim to identify potent TCM compounds as lead compounds of PKM...

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Main Authors: Chen, Kuan-Chung, Chen, Kuen-Bao, Chen, Hsin-Yi, Chen, Calvin Yu-Chian
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi Publishing Corporation 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096393/
https://ncbi.nlm.nih.gov/pubmed/25089263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/189495
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