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In Silico Investigation of Potential Pyruvate Kinase M2 Regulators from Traditional Chinese Medicine against Cancers

A recent research in cancer research demonstrates that tumor-specific pyruvate kinase M2 (PKM2) plays an important role in chromosome segregation and mitosis progression of tumor cells. To improve the drug development of TCM compounds, we aim to identify potent TCM compounds as lead compounds of PKM...

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Detalles Bibliográficos
Main Authors: Chen, Kuan-Chung, Chen, Kuen-Bao, Chen, Hsin-Yi, Chen, Calvin Yu-Chian
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096393/
https://ncbi.nlm.nih.gov/pubmed/25089263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/189495
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