Rictor/mTORC2Loss in the Myf5-lineage Reprograms Brown Fat Metabolism and Protects Mice against Obesity and Metabolic Disease

The in vivo functions of mTORC2, and the signaling mechanisms that control brown adipose tissue (BAT) fuel utilization and activity, are not well understood. Here, by conditionally deleting Rictorin the Myf5-lineage, we provide in vivo evidence that mTORC2 is dispensable for skeletal muscle developm...

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Bibliografiske detaljer
Main Authors: Hung, Chien-Min, Calejman, Camila Martinez, Sanchez-Gurmaches, Joan, Li, Huawei, Clish, Clary B., Hettmer, Simone, Wagers, Amy J., Guertin, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096327/
https://ncbi.nlm.nih.gov/pubmed/25001283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.007
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