Brown fat organogenesis and maintenance requires AKT1 and AKT2

OBJECTIVE: Understanding the signaling mechanisms that control brown adipose tissue (BAT) development is relevant to understanding energy homeostasis and obesity. The AKT kinases are insulin effectors with critical in vivo functions in adipocytes; however, their role in adipocyte development remains...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Metab
Main Authors: Sanchez-Gurmaches, Joan, Martinez Calejman, Camila, Jung, Su Myung, Li, Huawei, Guertin, David A.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480051/
https://ncbi.nlm.nih.gov/pubmed/30833219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.02.004
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