Brown fat AKT2 is a cold-induced kinase that stimulates ChREBP-mediated de novo lipogenesis to optimize fuel storage and thermogenesis

Brown adipose tissue (BAT) is a therapeutic target for metabolic diseases; thus, understanding its metabolic circuitry is clinically important. Many studies of BAT compare rodents mildly cold to those severely cold. Here, we compared BAT remodeling between thermoneutral and mild cold adapted mice, c...

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Détails bibliographiques
Publié dans:Cell Metab
Auteurs principaux: Sanchez-Gurmaches, Joan, Tang, Yuefeng, Jespersen, Naja Zenius, Wallace, Martina, Calejman, Camila Martinez, Gujja, Sharvari, Li, Huawei, Edwards, Yvonne JK, Wolfrum, Christian, Metallo, Christian M, Nielsen, Søren, Scheele, Camilla, Guertin, David A
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762420/
https://ncbi.nlm.nih.gov/pubmed/29153407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.10.008
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