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The mammalian response to virus infection is independent of small RNA silencing

A successful cellular response to virus infection is essential for evolutionary survival. In plants, arthropods, and nematodes, cellular antiviral defenses rely on RNA interference (RNAi). Interestingly, the mammalian response to virus is predominantly orchestrated through interferon (IFN)-mediated...

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Detalhes bibliográficos
Main Authors: Backes, Simone, Langlois, Ryan A., Schmid, Sonja, Varble, Andrew, Shim, Jaehee V., Sachs, David, tenOever, Benjamin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096324/
https://ncbi.nlm.nih.gov/pubmed/24953656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.05.038
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