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Targeted treatment for sonic hedgehog-dependent medulloblastoma

Novel treatment options, including targeted therapies, are needed for patients with medulloblastoma (MB), especially for those with high-risk or recurrent/relapsed disease. Four major molecular subgroups of MB have been identified, one of which is characterized by activation of the sonic hedgehog (S...

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Autor principal: Kieran, Mark W.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096181/
https://ncbi.nlm.nih.gov/pubmed/24951114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou109
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