Загрузка...
Aryl-substituted aminobenzimidazoles targeting the hepatitis C virus internal ribosome entry site
We describe the exploration of N1-aryl-substituted benzimidazoles as ligands for the hepatitis C virus (HCV) internal ribosome entry site (IRES) RNA. The design of the compounds was guided by the co-crystal structure of a benzimidazole viral translation inhibitor in complex with the RNA target. Stru...
Сохранить в:
| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096041/ https://ncbi.nlm.nih.gov/pubmed/24856063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.05.009 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|