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GLP1-derived nonapeptide GLP1(28–36)amide protects pancreatic β-cells from glucolipotoxicity

Type 2 diabetes, often associated with obesity, results from a deficiency of insulin production and action manifested in increased blood levels of glucose and lipids that further promote insulin resistance and impair insulin secretion. Glucolipotoxicity caused by elevated plasma glucose and lipid le...

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Bibliografiske detaljer
Main Authors: Liu, Zhengu, Stanojevic, Violeta, Brindamour, Luke J, Habener, Joel F
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096040/
https://ncbi.nlm.nih.gov/pubmed/22414687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-11-0328
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