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The key role of growth hormone — insulin — IGF-1 signaling in aging and cancer

Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors in aging. GH/Insulin/insulin-like growth factor 1 (IGF-1) signaling molecules that have been linked to longevity include daf-2 and InR and their homologues in mammals, and inactivation of the...

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Hlavní autoři: Anisimov, Vladimir N., Bartke, Andrzej
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095988/
https://ncbi.nlm.nih.gov/pubmed/23434537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.critrevonc.2013.01.005
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