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The key role of growth hormone — insulin — IGF-1 signaling in aging and cancer
Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors in aging. GH/Insulin/insulin-like growth factor 1 (IGF-1) signaling molecules that have been linked to longevity include daf-2 and InR and their homologues in mammals, and inactivation of the...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4095988/ https://ncbi.nlm.nih.gov/pubmed/23434537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.critrevonc.2013.01.005 |
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