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Constant pH Molecular Dynamics in Explicit Solvent with Enveloping Distribution Sampling and Hamiltonian Exchange

[Image: see text] We present a new computational approach for constant pH simulations in explicit solvent based on the combination of the enveloping distribution sampling (EDS) and Hamiltonian replica exchange (HREX) methods. Unlike constant pH methods based on variable and continuous charge models,...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Juyong, Miller, Benjamin T., Damjanović, Ana, Brooks, Bernard R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095908/
https://ncbi.nlm.nih.gov/pubmed/25061443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct500175m
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