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Construction and evaluation of a novel humanized HER2-specific chimeric receptor

INTRODUCTION: The human epidermal growth factor receptor 2 (HER2) represents one of the most studied tumor-associated antigens (TAAs) for cancer immunotherapy. The monoclonal antibody (mAb) trastuzumab has improved the outcomes of patients with HER2+ breast cancer. However, a large number of HER2+ t...

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Hlavní autoři: Sun, Meili, Shi, Huan, Liu, Chuanyong, Liu, Jie, Liu, Xianqiang, Sun, Yuping
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095682/
https://ncbi.nlm.nih.gov/pubmed/24919843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3674
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