Polygenic Scores Predict Alcohol Problems in an Independent Sample and Show Moderation by the Environment

Alcohol problems represent a classic example of a complex behavioral outcome that is likely influenced by many genes of small effect. A polygenic approach, which examines aggregate measured genetic effects, can have predictive power in cases where individual genes or genetic variants do not. In the...

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Autori principali: Salvatore, Jessica E., Aliev, Fazil, Edwards, Alexis C., Evans, David M., Macleod, John, Hickman, Matthew, Lewis, Glyn, Kendler, Kenneth S., Loukola, Anu, Korhonen, Tellervo, Latvala, Antti, Rose, Richard J., Kaprio, Jaakko, Dick, Danielle M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094936/
https://ncbi.nlm.nih.gov/pubmed/24727307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5020330
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