Bach1 Deficiency and Accompanying Overexpression of Heme Oxygenase-1 Do Not Influence Aging or Tumorigenesis in Mice

Oxidative stress contributes to both aging and tumorigenesis. The transcription factor Bach1, a regulator of oxidative stress response, augments oxidative stress by repressing the expression of heme oxygenase-1 (HO-1) gene (Hmox1) and suppresses oxidative stress-induced cellular senescence by restri...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Ota, Kazushige, Brydun, Andrey, Itoh-Nakadai, Ari, Sun, Jiying, Igarashi, Kazuhiko
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094857/
https://ncbi.nlm.nih.gov/pubmed/25050144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/757901
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki