Activation of HER3 Interferes with Antitumor Effects of Axl Receptor Tyrosine Kinase Inhibitors: Suggestion of Combination Therapy()

The Axl receptor tyrosine kinase (RTK) has been established as a strong candidate for targeted therapy of cancer. However, the benefits of targeted therapies are limited due to acquired resistance and activation of alternative RTKs. Therefore, we asked if cancer cells are able to overcome targeted A...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Torka, Robert, Pénzes, Kinga, Gusenbauer, Simone, Baumann, Christine, Szabadkai, István, Őrfi, Lászlȯ, Kéri, György, Ullrich, Axel
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094830/
https://ncbi.nlm.nih.gov/pubmed/24862757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.03.009
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky