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Azapropellanes with Anti-Influenza A Virus Activity

[Image: see text] The synthesis of several [4,4,3], [4,3,3], and [3,3,3]azapropellanes is reported. Several of the novel amines displayed low-micromolar activities against an amantadine-resistant H1N1 strain, but they did not show activity against an amantadine-sensitive H3N2 strain. None of the tes...

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Detalhes bibliográficos
Main Authors: Torres, Eva, Leiva, Rosana, Gazzarrini, Sabrina, Rey-Carrizo, Matías, Frigolé-Vivas, Marta, Moroni, Anna, Naesens, Lieve, Vázquez, Santiago
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094260/
https://ncbi.nlm.nih.gov/pubmed/25050174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500108s
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