Small Molecule that Reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia (T-ALL)

[Image: see text] Glucocorticoids are one of the most utilized and effective therapies in treating T-cell acute lymphoblastic leukemia. However, patients often develop resistance to glucocorticoids, rendering these therapies ineffective. We screened 9517 compounds, selected for their lead-like prope...

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Egile Nagusiak: Cantley, Alexandra M., Welsch, Matthew, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Kim, Mi-Yeon, Bauer, Andras, Ferrando, Adolfo, Stockwell, Brent R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2014
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094258/
https://ncbi.nlm.nih.gov/pubmed/25050160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500044g
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