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The molecular basis of T cell acute lymphoblastic leukemia
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and genetic alterations in transcription factors, signa...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461904/ https://ncbi.nlm.nih.gov/pubmed/23023710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61269 |
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