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Novel Hybrids of Natural Oridonin-Bearing Nitrogen Mustards as Potential Anticancer Drug Candidates

[Image: see text] A series of novel hybrids from natural product oridonin and nitrogen mustards were designed and synthesized to obtain more efficacious and less toxic antitumor agents. The antiproliferative evaluation showed that most conjugates were more potent than their parent compounds oridonin...

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Detalhes bibliográficos
Main Authors: Xu, Shengtao, Pei, Lingling, Wang, Chengqian, Zhang, Yun-Kai, Li, Dahong, Yao, Hequan, Wu, Xiaoming, Chen, Zhe-Sheng, Sun, Yijun, Xu, Jinyi
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094252/
https://ncbi.nlm.nih.gov/pubmed/25050168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500141f
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