Differentiated Troy(+) chief cells act as 'reserve' stem cells to generate all lineages of the stomach epithelium

Proliferation of the self-renewing epithelium of the gastric corpus occurs almost exclusively in the isthmus of the glands, from where cells migrate bi-directionally towards pit and base. The isthmus is therefore generally viewed as the stem cell zone. We find that the stem cell marker Troy is expre...

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Detalhes bibliográficos
Main Authors: Stange, Daniel E., Koo, Bon-Kyoung, Huch, Meritxell, Sibbel, Greg, Basak, Onur, Lyubimova, Anna, Kujala, Pekka, Bartfeld, Sina, Koster, Jan, Geahlen, Jessica H., Peters, Peter J., van Es, Johan H., van de Wetering, Marc, Mills, Jason C., Clevers, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094146/
https://ncbi.nlm.nih.gov/pubmed/24120136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.008
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