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Capping motifs stabilize the leucine-rich repeat protein PP32 and rigidify adjacent repeats

Capping motifs are found to flank most β-strand-containing repeat proteins. To better understand the roles of these capping motifs in organizing structure and stability, we carried out folding and solution NMR studies on the leucine-rich repeat (LRR) domain of PP32, which is composed of five tandem...

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Autors principals: Dao, Thuy P, Majumdar, Ananya, Barrick, Doug
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093955/
https://ncbi.nlm.nih.gov/pubmed/24659532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2462
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