NEMO Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Encoded vFLIP K13-Induced Gene Expression and Protection against Death Receptor-Induced Cell Death, and Its N-Terminal 251 Residues Are Sufficient for This Process

Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 was originally believed to protect virally infected cells against death receptor-induced apoptosis by interfering with caspase 8/FLICE activation. Subsequent studies revealed that K13 also activates the N...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Tolani, Bhairavi, Matta, Hittu, Gopalakrishnan, Ramakrishnan, Punj, Vasu, Chaudhary, Preet M.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2014
الموضوعات:
Virus-Cell Interactions
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093867/
https://ncbi.nlm.nih.gov/pubmed/24672029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00028-14
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