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Two Membrane-Associated Regions within the Nodamura Virus RNA-Dependent RNA Polymerase Are Critical for both Mitochondrial Localization and RNA Replication

Viruses with positive-strand RNA genomes amplify their genomes in replication complexes associated with cellular membranes. Little is known about the mechanism of replication complex formation in cells infected with Nodamura virus. This virus is unique in its ability to lethally infect both mammals...

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Main Authors: Gant, Vincent U., Moreno, Stephanie, Varela-Ramirez, Armando, Johnson, Kyle L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093860/
https://ncbi.nlm.nih.gov/pubmed/24696464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03032-13
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