Interaction of the Influenza A Virus Nucleocapsid Protein with the Viral RNA Polymerase Potentiates Unprimed Viral RNA Replication

The influenza A virus polymerase transcribes and replicates the eight virion RNA (vRNA) segments. Transcription is initiated with capped RNA primers excised from cellular pre-mRNAs by the intrinsic endonuclease of the viral polymerase. Viral RNA replication occurs in two steps: first a full-length c...

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Autores principales: Newcomb, Laura L., Kuo, Rei-Lin, Ye, Qiaozhen, Jiang, Yunyun, Tao, Yizhi Jane, Krug, Robert M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612335/
https://ncbi.nlm.nih.gov/pubmed/18945782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02293-07
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