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Sequence in the Influenza A Virus Nucleoprotein Required for Viral Polymerase Binding and RNA Synthesis

Many proposed mechanisms for influenza A viral RNA synthesis include an interaction of the nucleoprotein (NP) with the viral polymerase. To identify an NP sequence required for this interaction, we used the cryoelectron microscopic structure of an influenza virus miniribonucleoprotein as a guide for...

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Detalhes bibliográficos
Main Authors: Marklund, Jesper K., Ye, Qiaozhen, Dong, Jinhui, Tao, Yizhi Jane, Krug, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416340/
https://ncbi.nlm.nih.gov/pubmed/22532672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00014-12
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