Hepatitis C Virus NS5A Hijacks ARFGAP1 To Maintain a Phosphatidylinositol 4-Phosphate-Enriched Microenvironment

Phosphatidylinositol 4-phosphate (PI4P) is well known to be upregulated during hepatitis C virus (HCV) replication. The role of PI4 kinases in HCV has been extensively investigated. Whether the PI4P phosphatase Sac1 is altered by HCV remains unclear. Here, we identified ARFGAP1 to be a novel host fa...

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Autores principales: Li, Hongyan, Yang, Xiaojie, Yang, Guangbo, Hong, Zhi, Zhou, Liya, Yin, Peiqi, Xiao, Yan, Chen, Lingyi, Chung, Raymond T., Zhang, Leiliang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093857/
https://ncbi.nlm.nih.gov/pubmed/24623438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03738-13
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