Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV

The accumulation of lipid droplets (LD) is frequently observed in hepatitis C virus (HCV) infection and represents an important risk factor for the development of liver steatosis and cirrhosis. The mechanisms of LD biogenesis and growth remain open questions. Here, transcriptome analysis reveals a s...

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Publicat a:Nat Commun
Autors principals: Akil, Abdellah, Peng, Juan, Omrane, Mohyeddine, Gondeau, Claire, Desterke, Christophe, Marin, Mickaël, Tronchère, Hélène, Taveneau, Cyntia, Sar, Sokhavuth, Briolotti, Philippe, Benjelloun, Soumaya, Benjouad, Abdelaziz, Maurel, Patrick, Thiers, Valérie, Bressanelli, Stéphane, Samuel, Didier, Bréchot, Christian, Gassama-Diagne, Ama
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947189/
https://ncbi.nlm.nih.gov/pubmed/27417143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12203
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