Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV

The accumulation of lipid droplets (LD) is frequently observed in hepatitis C virus (HCV) infection and represents an important risk factor for the development of liver steatosis and cirrhosis. The mechanisms of LD biogenesis and growth remain open questions. Here, transcriptome analysis reveals a s...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Akil, Abdellah, Peng, Juan, Omrane, Mohyeddine, Gondeau, Claire, Desterke, Christophe, Marin, Mickaël, Tronchère, Hélène, Taveneau, Cyntia, Sar, Sokhavuth, Briolotti, Philippe, Benjelloun, Soumaya, Benjouad, Abdelaziz, Maurel, Patrick, Thiers, Valérie, Bressanelli, Stéphane, Samuel, Didier, Bréchot, Christian, Gassama-Diagne, Ama
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947189/
https://ncbi.nlm.nih.gov/pubmed/27417143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12203
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