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Septin 9 and phosphoinositides regulate lysosome localization and their association with lipid droplets
Summary: The accumulation of lipid droplets (LDs) in the liver is a hallmark of steatosis, which is often associated with lysosomal dysfunction. Nevertheless, the underlying mechanisms remain unclear. Here, using Huh7 cells loaded with oleate as a model to study LD metabolism, we show that cellular...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2022-05-01
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| Colecção: | iScience |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2589004222005582 |
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