Cargando...

Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression.

Chronic exposure of HIT-T15 beta cells to elevated glucose concentrations leads to decreased insulin gene transcription. The reduction in expression is accompanied by diminished binding of a glucose-sensitive transcription factor (termed GSTF) that interacts with two (A+T)-rich elements within the 5...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Olson, L K, Sharma, A, Peshavaria, M, Wright, C V, Towle, H C, Rodertson, R P, Stein, R
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC40937/
https://ncbi.nlm.nih.gov/pubmed/7568086
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!