HSV-1 ICP0: An E3 Ubiquitin Ligase That Counteracts Host Intrinsic and Innate Immunity

The herpes simplex virus type 1 (HSV-1) encoded E3 ubiquitin ligase, infected cell protein 0 (ICP0), is required for efficient lytic viral replication and regulates the switch between the lytic and latent states of HSV-1. As an E3 ubiquitin ligase, ICP0 directs the proteasomal degradation of several...

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Bibliographic Details
Main Authors: Lanfranca, Mirna Perusina, Mostafa, Heba H., Davido, David J
Format: Artigo
Language:Inglês
Published: MDPI 2014
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092860/
https://ncbi.nlm.nih.gov/pubmed/24852129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells3020438
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