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A quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitro
The ubiquitin–proteasome system is an essential cellular process that plays a fundamental role in the regulation of protein stability. This pathway is tightly controlled by a sequential cascade of enzymatic steps that culminates in the formation of a poly-ubiquitin chain onto the substrate protein t...
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| Veröffentlicht in: | Methods |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Academic Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655872/ https://ncbi.nlm.nih.gov/pubmed/25862948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2015.04.004 |
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