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A quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitro

The ubiquitin–proteasome system is an essential cellular process that plays a fundamental role in the regulation of protein stability. This pathway is tightly controlled by a sequential cascade of enzymatic steps that culminates in the formation of a poly-ubiquitin chain onto the substrate protein t...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Boutell, Chris, Davido, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655872/
https://ncbi.nlm.nih.gov/pubmed/25862948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2015.04.004
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